平安！ 发表于 2011-11-9 19:57
8 I1 \5 `5 g2 HPazopanib (100 mg/kg/day free base equivalent)
; A2 c1 z2 d( K$ Z8 i2 J' A$ {* l: I 这是个已经在美国上市的老药了，能下载到正式药物使用说明书英文版。& s2 N0 Y( ?+ H) C" g$ N3 h4 V
搜索了一下，原料一大堆。: f# T( d( k r4 O" y3 O b1 |
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对不起！100mg/kg是用于移植瘤的，我弄错了。! U- H u P$ q2 H) F9 x' @
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以下是正版说明书的推荐用量。
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+ G% g6 }; ?% [--------------------- DOSAGE AND ADMINISTRATION ----------------: J4 Q; n" M0 M, a1 l; w6 l
* 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal). (2.1) ' s. O4 t, F# N9 V/ v: B5 H! I9 l/ e
* Baseline moderate hepatic impairment – 200 mg orally once daily. Not recommended in patients with severe hepatic impairment. (2.2) " y; s' G1 A" {
---------------------DOSAGE FORMS AND STRENGTHS --------------
! h# K1 K, T) N7 l0 ^1 y200 mg tablets. (3)
1 d, @' O( s. D) K/ u3 b; C$ }! x-------------------------------CONTRAINDICATIONS------------------------ |
显身卡
