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Cancer Treatments and Ketosis
It isn't always successful, but as the newest research is showing, ketosis can be beneficial for many cancer cases. And as an added benefit, using ketogenic diets in cancer treatments actually supports and strengthens the patient's overall health.
In this paper titled "Targeting energy metabolism in brain cancer with calorically restricted ketogenic diets" the authors conclude:
"The CRKD (calorie restricted ketogenic diet) is effective in managing brain tumor growth in animal models and in patients, and appears to act through antiangiogenic, anti-inflammatory, and proapoptotic mechanisms."
Translation: Calorie restricted ketogenic diets were effective in stopping the growth of brain tumor in both animals and humans, and they seem to work by stopping the tumor from creating new arteries for supplying itself with blood, reducing inflammation, and restoring the normal cell death mechanisms. (Cancer cells are known to have the ability to avoid the normal mechanisms by which damaged cells die).
And in this paper, Dr. Eugene Fine of the Albert Einstein College of Medicine hypothesizes that ketone bodies stop cancers by changing the availability of energy processes in cancer cells. A preliminary paper from Dr. Fine's team was published and the summary of results states:
"Preliminary data demonstrate that an insulin-inhibiting diet is safe and feasible in selected patients with advanced cancer. The extent of ketosis, but not calorie deficit or weight loss, correlated with stable disease or partial remission."
There's a podcast interview with Dr. Fine here.
Following the Ketogenic Diet For Cancer
The diet prescription for those with cancer is basically the same as any ketogenic diet, in that it is a high fat, moderate protein, very low carb protocol. However, there are some differences. Calories and certain foods which are insulin stimulating are also restricted and certain target levels of ketones and blood sugar must be met.
As Dr. Thomas Seyfried describes in his book "Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer", there are target ranges of blood glucose levels and ketone levels that are optimal for stopping the growth of the cancer.
Dr. Seyfried recommends implementing a restricted ketogenic diet and balancing blood sugar and ketone levels in a ratio he calls the glucose to ketone ratio, or the G/K index. He spoke about using a ketogenic diet to treat cancer at the 2012 Ancestral Health Symposium. And here's a recent independent paper highlighting that an increase in the uptake of glucose in nonmalignant human breast cells "activates known oncogenic pathways to induce malignant phenotype" (i.e. cancerous cells), which reinforces the idea that an increase in the cellular burning of sugar, a process called glycolysis, is a factor in the activation of cancer.
Checking blood sugar and ketones levels requires using a blood sugar and blood ketone meter. There are many different brands of blood sugar meters, and just recently, several brands of blood ketone meters have been put on the market. The Precision Xtra Advanced Diabetes Management System or the Nova Max Plus Blood Glucose Monitoring System brands offer a meter which can track both blood sugar and blood ketones with different strips. Be aware that the ketone strips are expensive.
There's an comprehensive article here by Dr. Seyfried et al on how a ketogenic diet is implemented in cases of certain kinds of cancer.
Miriam Kalamian, a nutritionist with a practice focused on educating and supporting implementation of the Ketogenic Diet for cancer and other metabolic diseases offers phone consultations. And I would also recommend that your doctor or a knowledgable nutritionist be involved as much as possible in the implementation of a ketogenic diet for cancer.
I have written an eBook with more information about using a restricted ketogenic diet to destroy cancer. It's available here, or click on the book cover image. |
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